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Quantitative high-pressure liquid chromatographic determination of thimerosal in pharmaceutical formulations

C C Fu, M J Sibley

Journal of Pharmaceutical Sciences

|May 1, 1977

Abstract:

A quantitative high-pressure liquid chromatographic method an anion-exchange resin column and an aqueous perchlorate solution as the mobile phase is employed for the determination of thimerosal in pharmaceutical formulations. With a liquid formulation containing large amounts of edetate disodium, calcium chloride is used for complexation to eliminate the interference from edetate disodium.

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