Recent progress in the molecular biology of the cloned N-acetylglucosaminyltransferases

Several genes which code for the N-acetylglucosaminyltransferases have been cloned and characterized. Physiological and pathophysiological roles of the genes still remain to be elucidated but accumulated evidence suggests that the N-acetylglucosaminyltransferase genes are implicated in differentiation, morphogenesis and cancer metastasis.