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The relationship between parent and offspring comorbid disorders

V Johnson1

  • 1Center of Alcohol Studies, Rutgers University, Piscataway, NJ 08854, USA.

Journal of Substance Abuse
|January 1, 1995
PubMed
Summary
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This study on 1,201 young adults found that while substance abuse is common, comorbidity with depression or antisocial personality is rare. Findings partially support the depression spectrum disease hypothesis regarding family history and individual disorders.

Area of Science:

  • Psychiatry
  • Addiction Medicine
  • Behavioral Science

Background:

  • Substance abuse and mental health disorders often co-occur.
  • Winokur's depression spectrum disease hypothesis suggests a link between parental and offspring disorders.
  • Understanding comorbidity is crucial for effective treatment strategies.

Purpose of the Study:

  • To investigate the comorbidity of substance abuse, depression, and antisocial behaviors in young adults.
  • To examine the influence of parental history of alcoholism and depression on offspring psychopathology.
  • To evaluate the support for Winokur's depression spectrum disease hypothesis.

Main Methods:

  • A community sample of 1,201 young adults was assessed.
  • Data collected included personal history of alcohol, drug abuse/dependence, depression, and antisocial behaviors.

Related Experiment Videos

  • Parental history of alcoholism and psychiatric disorders was also documented.

    • Main Results:

    • 35% of subjects exhibited alcohol abuse/dependence; 14% exhibited marijuana or cocaine abuse/dependence.
    • Comorbidity with depression or antisocial personality was infrequent in both subjects and parents.
    • Over one-third of subjects had no family history or personal disorder; 20% had issues in both themselves and parents.

    Conclusions:

    • Findings offer partial support for the depression spectrum disease hypothesis.
    • Children from depressed-only families showed a higher likelihood of substance abuse than depression.
    • Children from alcoholic-only families showed a lower likelihood of depression than substance abuse.