Primary intraocular lymphoma mimicking late postoperative endophthalmitis

We treated a 65-year old woman with diffuse uveitis and an intraocular mass. The diffuse uveitis resolved with the administration of corticosteroids, but the intraocular mass did not respond to treatment. A transscleral biopsy of the lesion was performed. Histopathological study revealed non-Hodgkin's large-cell lymphoma. Immunohistochemical analysis showed that the tumor cells were derived from B-cells. The intraocular mass diminished after radiation therapy. The transscleral biopsy proved useful in establishing the correct diagnosis.