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Computer-assisted semen analysis parameters in men with varicocele: is surgery helpful?
F R Parikh1, S A Kamat, G G Kodwaney
1Department of Infertility Management and Assisted Reproduction, Jaslok Hospital and Research Centre, Bombay, India.
Fertility and Sterility
|September 1, 1996
Summary
Varicocelectomy significantly improves sperm quality in infertile men, with computer-assisted semen analysis (CASA) enabling accurate evaluation. Post-surgery, 50% of men achieved pregnancy, highlighting varicocelectomy
Area of Science:
- Reproductive Medicine
- Andrology
- Urology
Background:
- Varicocele is a common cause of male infertility.
- Sperm quality is often impaired in men with varicocele.
- Objective assessment of sperm parameters is crucial for diagnosis and treatment planning.
Purpose of the Study:
- To evaluate the effectiveness of varicocelectomy in improving sperm characteristics.
- To assess fertility outcomes after varicocelectomy.
- To determine the utility of computer-assisted semen analysis (CASA) in monitoring treatment response.
Main Methods:
- Semen samples from 49 infertile men with varicocele were analyzed using CASA.
- Sperm parameters of 26 men who underwent varicocelectomy were assessed preoperatively and at 3, 6, and 9 months postoperatively.
- Pregnancy outcomes (natural or assisted conception) were recorded.
Main Results:
- Men with varicocele exhibited significantly lower sperm count, motility, and normal morphology.
- Varicocelectomy led to significant improvements in sperm count, motility, and morphology.
- Post-surgery, 46.2% of men achieved normal semen parameters, and the overall pregnancy rate was 50%.
Conclusions:
- Computer-assisted semen analysis (CASA) offers accurate quantitative assessment of semen parameters in varicocele patients.
- Varicocelectomy is an effective treatment for varicocele-related infertility, improving semen quality and leading to a 50% pregnancy rate.