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Endometrial stripe thickness as a predictor of ectopic pregnancy
1Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, USA.
Objective:
To evaluate the potential utility of endometrial stripe thickness in predicting pregnancy outcome in women with an hCG less than a discriminatory zone.
Design:
Retrospective case review.
Setting:
University emergency department.
Patients:
Women who presented with symptomatic early pregnancies after a spontaneous conception with an hCG level less than a discriminatory zone evaluated to rule out an ectopic pregnancy (EP).
Interventions:
Measure endometrial stripe thickness by transvaginal ultrasound.
Main Outcome Measures:
Initial endometrial stripe thickness was correlated to eventual pregnancy outcomes.
Results:
The mean initial endometrial stripe thickness of patients eventually diagnosed with an intrauterine pregnancy (13.42 +/- 0.68 mm), spontaneous abortion (9.28 +/- 0.88 mm), and an EP (5.95 +/- 0.35 mm) were all statistically different from each other. Ninety-seven percent of pregnancies found to have an endometrial stripe thickness < or = 8 mm were abnormal (EP or spontaneous abortion).
Conclusions:
This study suggest a role of the evaluation of the endometrial stripe thickness in the detection of abnormal pregnancies in patients presenting for evaluation of a symptomatic early pregnancy with an hCG below a discriminatory zone. Initial endometrial stripe thickness measured in patients with an EP is significantly thinner than in those with an intrauterine pregnancy.