Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Progression02:07

Tumor Progression

7.5K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.5K
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

4.9K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
4.9K
The Nucleolus02:55

The Nucleolus

10.4K
The nucleolus is the most prominent substructure of the nucleus. When it was first discovered, it was considered to be an isolated organelle that forms fibrils and granules. In 1931, the relationship between the nucleolus and chromosomes was first described by Heitz. He observed that the appearance and size of nucleolus varies depending on the stage of the cell cycle. He also noticed constricted regions on different chromosomes clustered together at definite cell cycle stages. These regions,...
10.4K
Reaction Rate02:53

Reaction Rate

65.6K
The rate of reaction is the change in the amount of a reactant or product per unit time. Reaction rates are therefore determined by measuring the time dependence of some property that can be related to reactant or product amounts. Rates of reactions that consume or produce gaseous substances, for example, are conveniently determined by measuring changes in volume or pressure.
The mathematical representation of the change in the concentration of reactants and products, over time, is the rate...
65.6K
Voltaic/Galvanic Cells02:47

Voltaic/Galvanic Cells

63.9K
Spontaneous Chemical Reactions
Spontaneous redox reactions occur abundantly in nature. The chemical reaction occurring in a disposable AA battery powering our remote controls is one such example of a spontaneous redox reaction. Another example is the immersion of coiled copper wire into an aqueous silver nitrate solution. The reaction shows a gradual, visually impressive color change from colorless to bright blue and the formation of a grey precipitate on the copper wire. In this experiment,...
63.9K
Measuring Reaction Rates03:09

Measuring Reaction Rates

31.2K
Polarimetry finds application in chemical kinetics to measure the concentration and reaction kinetics of optically active substances during a chemical reaction. Optically active substances have the capability of rotating the plane of polarization of linearly polarized light passing through them—a feature called optical rotation. Optical activity is attributed to the molecular structure of substances. Normal monochromatic light is unpolarized and possesses oscillations of the electrical...
31.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Decreased physical performance of congenic mice with mismatch between the nuclear and the mitochondrial genome.

Genes & genetic systems·1998
Same author

Identification of a new intermediate state that binds but not activates transducin in the bleaching process of bovine rhodopsin.

FEBS letters·1998
Same author

Contribution of foregut endoderm to tooth initiation of mandibular incisor in rat embryos.

European journal of oral sciences·1998
Same author

Interleukin-1 receptor antagonist inhibits transient increase of plasma corticosterone in the initial phase of trimethyltin-induced hippocampal necrosis.

Neurotoxicology·1998
Same author

Glomerulopathy due to chronic infection of Propionibacterium acnes in a patient with Felty's syndrome.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·1998
Same author

Crescentic glomerulonephritis accompanied by myeloperoxidase-antineutrophil cytoplasmic antibodies in a patient having myelodysplastic syndrome with trisomy 7.

American journal of kidney diseases : the official journal of the National Kidney Foundation·1998
Same journal

[Let's present at a regional meeting].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[Editor's Note].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[Notice for Members].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[The Proceedings of the 250th Kyushu Regional Meeting of the Japanese Society of Neurology].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[The Proceedings of the 116th Tohoku Regional Meeting of the Japanese Society of Neurology].

Rinsho shinkeigaku = Clinical neurology·2026
Same journal

[Metagenomic analysis for central nervous system infections: clinical utility and future directions].

Rinsho shinkeigaku = Clinical neurology·2026
See all related articles

Related Experiment Videos

[Progressive supranuclear palsy]

H Imai1

  • 1Department of Neurology, Juntendo University School of Medicine.

Rinsho Shinkeigaku = Clinical Neurology
|December 1, 1995
PubMed
Summary
This summary is machine-generated.

Progressive supranuclear palsy (PSP) is a neurological disorder. Pure akinesia, a condition affecting movement, speech, and handwriting, may represent an early stage of PSP.

Related Experiment Videos

Area of Science:

  • Neurology
  • Neuroscience
  • Pathology

Background:

  • Progressive supranuclear palsy (PSP) was first described in 1964.
  • A related syndrome of levodopa-unresponsive pure akinesia was identified in 1974.
  • This syndrome affects gait, handwriting, and speech.

Observation:

  • Pure akinesia presents without rigidity or tremor.
  • Japanese studies suggest pure akinesia may precede oculomotor deficits in PSP.
  • This indicates a potential early manifestation of PSP.

Findings:

  • The syndrome of pure akinesia/PSP is proposed.
  • Evidence suggests a link between pure akinesia and PSP.
  • This challenges the traditional definition of PSP.

Implications:

  • Understanding pure akinesia's relationship to PSP can aid early diagnosis.
  • Further research into the pathogenesis and etiology of PSP and related conditions is crucial.
  • This may lead to new therapeutic strategies for PSP and similar disorders.