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Parasitic infections presenting as prolonged fevers

M F Abdel Wahab1, T A Younis, I A Fahmy

  • 1Department of Tropical Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Journal of the Egyptian Society of Parasitology
|August 1, 1996
PubMed
Summary

Parasitic infections caused 16% of fevers of undetermined origin (FUO). Serology and ultrasonography were crucial for diagnosing parasitic diseases like schistosomiasis, fascioliasis, and amoebic liver abscess.

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Area of Science:

  • Tropical Medicine
  • Infectious Diseases
  • Parasitology

Background:

  • Fever of undetermined origin (FUO) presents a diagnostic challenge.
  • Parasitic infections are a significant, yet often overlooked, cause of FUO.

Purpose of the Study:

  • To investigate the prevalence and diagnostic approaches for parasitic causes of FUO.
  • To evaluate the utility of serological tests and ultrasonography in diagnosing parasitic infections.

Main Methods:

  • Analysis of 187 FUO cases over two years.
  • Utilized complete blood count, stool examination, rectal snips, ELISA, IHAT, IFAT, and abdominal ultrasonography.
  • Included 30 confirmed parasitic cases and 10 controls.

Main Results:

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  • Parasitic infections accounted for 16% (30/187) of FUO cases.
  • Acute schistosomiasis and fascioliasis presented similar symptoms; serology differentiated them.
  • Ultrasonography aided in diagnosing amoebic liver abscess and hydatid cysts, with serology essential for confirmation.
  • Toxoplasmosis and malaria presented with atypical symptoms, diagnosed via serology and blood smears, respectively.

Conclusions:

  • Parasitic infections are a common cause of FUO, necessitating specific diagnostic considerations.
  • A combination of serological tests and imaging modalities like ultrasonography is vital for accurate diagnosis.
  • Early and accurate diagnosis of parasitic FUO is crucial for effective management and preventing complications.