[Activity of key enzymes of the glycolytic and pentose phosphate pathways in plasmid-containing Staphylococci]

Comparative data concerning enzyme activities of central metabolic pathways in pathogenic staphylococcus strains, containing and not containing plasmids of resistance to different antibiotics has been presented. An increase in the activity of key enzymes of glycolytic pathway: 6-phosphofructokinase, fructose-1,6-biophosphate aldolase, lactate dehydrogenase, and a decrease in the activity of enzymes of the pentose phosphate cycle: glucose-6-phosphate dehydrogenase in antibiotic resistant strains, were defined.