Related Experiment Video
Updated: Jul 22, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
Published on: May 17, 2024
[Neurofibromatosis type I (NF1): peculiarities and complications]
1Servicio de Neurologia, Hospital Infantil La Paz, Madrid.
Abstract:
The clinical, radiological and genetic peculiarities of neurofibromatosis type 1 (NF1) or the von Recklinghausen disease are shown. The most common complications of this syndrome are presented. These are optic pathways gliomas and some other tumors of the nervous system and of any other location in the body; oseous alterations with skoliosis, pseudoarthrosis and facial dysplasias as the most important; aqueductal stenosis that frequently appears at the puberty or at adult life; an intellectual level lower than their brothers and sisters without NF1, and some less frequent complications such as endocrinological disorders and corpus callosum agenesis.
More Related Videos
Related Concept Videos
Neurulation
Notch Signaling Pathway
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
Neurogenesis and Regeneration of Nervous Tissue
Cranial Nerves: Overview and Anatomy
Cranial Nerves: Types Part I
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Multiple Sclerosis l: Introduction

