Tracheal resection and anastomosis for an intratracheal chondroma in a ball python

A 9-year-old female ball python was evaluated for lethargy and respiratory compromise. Radiographic and endoscopic examination revealed a 1-cm intratracheal mass occluding the tracheal lumen. A partial tracheal resection and anastomosis was performed to remove the mass. On histologic examination, the mass was determined to be an intratracheal chondroma. Eosinophilic cytoplasmic inclusions observed within the tissue were calcium deposits. Electron microscopy was used to differentiate these from viral inclusion bodies often associated with neoplasms in reptiles. Endoscopic evaluation of the trachea 5 weeks after surgery revealed complete healing and minimal stenosis at the surgery site. Indications of tumor regrowth were not evident. Clinical signs of recurrence of respiratory compromise had not been observed 9 months after surgery.