[Disseminated histiocytosis X in an adult patient]

Patient was a 69 year old white female who presented with diffuse brownish-reddish and normal skin colored nodules of a diameter ranging from 0.5-4 cm. Histologic examination showed histiocytosis X. Despite the retinoid-PUVA, and combination of glucocorticoid and chemotherapy the disease progressed and in 8 months after the appearance of the skin lesions the patient expired. The authors briefly summarise the clinical, histological features of histiocytosis X and the therapeutic possibilities.