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Measurement of flow dynamics in the microcirculation
Medical Instrumentation
|May 1, 1977
Summary
This study details a method for measuring microcirculation flow using optical signals from photometers. The technique accurately quantifies blood flow dynamics in small vessels and is applied to human skin studies.
Area of Science:
- Physiology
- Biomedical Engineering
- Optical Imaging
Background:
- Microcirculation blood flow measurement is crucial for understanding physiological processes.
- Accurate quantification of flow in small vessels presents technical challenges.
Purpose of the Study:
- To present a methodology for measuring microcirculation flow using optical signal processing.
- To demonstrate the capability of quantifying pulsatile flow and vasomotion.
Main Methods:
- Utilizes photometers to process optical signals from microvessels.
- Employs television recordings for simultaneous capillary flow determination.
- A specialized correlator analyzes dynamic flow responses.
Main Results:
- Reliable flow records obtained from capillaries to 100 micrometer vessels.
- Simultaneous flow determination in multiple capillaries is feasible.
- Dynamic response sufficient for quantifying pulsatile flow and vasomotion.
Conclusions:
- The described optical signal processing methodology enables accurate microcirculation flow measurement.
- The technique is applicable to studying physiological maneuvers in human skin.