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Interleukin-8 gene expression in Staphylococcus aureus-infected endothelial cells
1Department of Pathology, Albert Einstein College of Medicine, Bronx, New York 104611, USA.
Infection and Immunity
|August 1, 1996
Abstract:
Interleukin-8 (IL-8) plays a crucial role in the migration of neutrophils to bacterium-infected sites. This study investigated IL-8 induction in Staphylococcus aureus-infected endothelial cells (EC). We observed that S. aureus-infected EC were induced to express both IL-8 mRNA and protein, which can promote transmigration of neutrophils across an EC monolayer.