Related Experiment Video
Updated: Aug 17, 2026
Mongolian Gerbils as an Animal Model of Wound Healing
Published on: January 6, 2023
[Histopathological study on corneal incisions of radial keratotomy]
1Zongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou.
Objective:
The study was designed to improve the safety and predictability of radial keratotomy (RK).
Method:
Penetrating keratoplasty was performed on two eyes following RK for 2 months and 2 years respectively and their corneal buttons were studied histopathologically.
Results:
The study revealed that at 2 months, there was only bridge-like healing of corneal epithelium, and oblique "V"-shaped, discontinuous or shallow incisions were seen, at 2 years, the healing process of partial incisions had not completed, and epithelial emboli were seen in the deep part of some incisions.
Conclusion:
Postoperatively, the incisions of RK are unstable for quite a long time. The RK incisions may influence other corneal surgeries performed on the same cornea in the future and are directly related to the healing and refractive outcome of RK. It is important to standardize the operative techniques.
