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[Hypomagnesemic and hypocalcemic coma, convulsions and ocular motility disorders after chemotherapy with platinum
C Bachmeyer1, Y Decroix, J Médioni
1Service de médecine interne, hôpital Hôtel-Dieu, Paris, France.
La Revue De Medecine Interne
|January 1, 1996
Abstract:
We describe a case of neurologic manifestations including coma, convulsion and eye movement disorders, associated with hypomagnesemia and hypocalcemia in a patient treated with cisplatin for an ovarian adenocarcinoma. Pathophysiological mechanisms involve renal tubular damage leading to renal magnesium wasting and related hypocalcemia.