Related Experiment Videos
[Coronary artery bypass with extracorporeal circulation in a patient with hemophilia B]
J G Bukowski1, J L De Brux, B Ganascia
1Département d'anesthésie-réanimation chirurgicale, CHU, Angers, France.
Insights
This study demonstrates successful quadruple coronary bypass grafting in a patient with factor IX deficiency (Christmas disease). Prophylactic factor IX concentrate infusions effectively prevented excessive bleeding, ensuring a safe surgical outcome.
Area of Science:
- Cardiovascular Surgery
- Hematology
- Coagulation Disorders
Background:
- Factor IX deficiency (Christmas disease) presents a significant bleeding risk for surgical patients.
- Coronary artery disease requiring surgical intervention necessitates careful management of coagulation status.
Observation:
- A 64-year-old patient diagnosed with factor IX deficiency was scheduled for quadruple coronary bypass grafting due to angina pectoris.
- The patient received factor IX concentrate infusions starting preoperatively and continuing for 19 days post-surgery.
Findings:
- The surgical procedure and cardiopulmonary bypass were performed using standard protocols without modifications for the bleeding disorder.
- No intraoperative or postoperative hemorrhagic complications were observed, indicating effective bleeding control.
Implications:
- This case highlights the feasibility and safety of major cardiac surgery in patients with factor IX deficiency.
- Effective perioperative management with factor IX concentrates can mitigate bleeding risks, allowing for necessary surgical interventions.
Abstract:
A 64-year-old patient with factor IX deficiency (Christmas disease) underwent quadruple coronary bypass grafting for angina pectoris. Excessive bleeding was prevented by infusion of factor IX concentrates from one day before surgery until the 19th postoperative day. The surgical procedure and the cardiopulmonary bypass were carried out in the same manner as in patients without any haemorrhagic disorder. No haemorrhagic complication occurred, neither during nor after the operation.