[Kinetics and differentiation of monocytes in man (author's transl)]

This paper gives a short review of the monocytopoiesis in the bone marrow, the kinetics of monocytes in the blood, the differentiation of monocytes in the tissue and presents new data on monocyte transit time through the peripheral blood. Monocyte kinetics were studied in three hematologically normal persons, four patients with Hodgkin's disease and four patients with chroniclymphocytic leukemia using 3H-TdR-pulse-injection or 3H-TdR continuous infusion. The average value of the mean blood monocyte transit time was 25.1 hours. The mean blood transit times of haematologically normal persons and patients with lymphatic disorders did not differ significantly.