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Minocycline-induced liver injury
A Malcolm1, T R Heap, R P Eckstein
1Department of Gastroenterology, Royal North Shore Hospital, Sydney, Australia.
The American Journal of Gastroenterology
|August 1, 1996
Summary
Minocycline, a tetracycline derivative, may cause liver injury, including acute hepatitis and chronic hepatitis. Some patients also showed autoimmune markers like anti-nuclear antibodies.
Area of Science:
- Hepatology
- Pharmacology
- Immunology
Background:
- Tetracycline antibiotics are known for potential liver toxicity, including fatty liver and cholestasis.
- Minocycline, a semi-synthetic tetracycline derivative, is generally considered less hepatotoxic.
- Emerging evidence suggests minocycline may also pose risks to liver health.
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