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Updated: Aug 15, 2026

Methods for Acute and Subacute Murine Hindlimb Ischemia
Published on: June 21, 2016
The influence of age on long-term survival pattern of patients operated on for lower limb ischaemia
S Aune1, S R Amundsen, A Trippestad
1Department of Surgery, Haukeland University Hospital, Bergen, Norway.
Objective:
To study the long-term survival patterns of patients subjected to surgery for lower limb ischaemia.
Design:
A retrospective clinical study.
Setting:
University Hospital.
Materials:
A series of 1411 patients older than 50 years operated on for all stages of lower limb ischaemia.
Chief Outcome Measures:
Observed and expected long-term survival rates were calculated. Relative survival, defined as the ratio of the observed to the expected survival rates, was studied for age influence.
Main Results:
The observed 10 year survival rate of 26% was significantly lower than the expected of 49%. Although women were 8 years older than men at the time of the operation they had similar long-term survival and relative survival. An inverse proportionality was found between the patient's age at the time of the operation and relative survival. The young patients experienced a 10 year mortality rate three to four times the expected, while the older had a mortality that was elevated 25-50% from the expected.
Conclusions:
Patients operated on for lower limb ischaemia experience a significantly lower long-term survival than that of a demographically matched population. This relative survival is significantly influenced by the patient's age at the time of the operation.
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