Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Retinoblastoma

R M Ellsworth

    Modern Problems in Ophthalmology
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    This study reviews modern retinoblastoma (a childhood eye cancer) diagnosis and treatment, including imaging, differential diagnoses, and radiation therapy complications. Newer genetic insights and chemotherapy protocols are also discussed for improved outcomes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    STUDIES ON THE PERMEABILITY OF MEMBRANES : II. DETERMINATION OF IONIC TRANSFER NUMBERS IN MEMBRANES FROM CONCENTRATION CHAINS.

    The Journal of general physiology·2009
    Same author

    [Ophthalmological surgery education. 23. Evisceration].

    Klinische Monatsblatter fur Augenheilkunde·1996
    Same author

    Parents with unilateral retinoblastoma: their affected children.

    The British journal of ophthalmology·1996
    Same author

    Orbital rhabdomyosarcoma: treatment or overtreatment.

    Ophthalmic genetics·1995
    Same author

    Unilateral retinoblastoma: new intraocular tumours after treatment.

    The British journal of ophthalmology·1994
    Same author

    Trilateral retinoblastoma--incidence and outcome: a decade of experience.

    International journal of radiation oncology, biology, physics·1994
    Same journal

    Scleral buckling in 2 1/2 to 11-month-old premature infants with retinal detachment associated with acute retrolental fibroplasia.

    Modern problems in ophthalmology·1979
    Same journal

    [Treatment of complications of venous retinal thromboses with argon laser].

    Modern problems in ophthalmology·1979
    Same journal

    Diabetic vitreous hemorrhage and its relationship to hypoglycemia.

    Modern problems in ophthalmology·1979
    Same journal

    Removal of foreign body encapsulated in the macula.

    Modern problems in ophthalmology·1979
    Same journal

    Comparison of temperature measurements and fundus reflectometry in laser coagulation.

    Modern problems in ophthalmology·1979
    Same journal

    Prophylactic photocoagulation of the fellow eye in exudative senile maculopathy. A preliminary report.

    Modern problems in ophthalmology·1979
    See all related articles

    Area of Science:

    • Ophthalmology
    • Pediatric Oncology
    • Medical Imaging
    • Radiation Oncology
    • Genetics

    Background:

    • Retinoblastoma diagnosis and treatment have evolved, presenting challenges in differential diagnosis.
    • Misinterpretation of "cure rate" has led to treatment misconceptions, particularly for unilateral disease.
    • Advancements in understanding retinoblastoma genetics and treatment modalities are crucial.

    Purpose of the Study:

    • To discuss updated concepts in retinoblastoma diagnosis and treatment.
    • To evaluate diagnostic tools like ultrasonography, EMI scanning, and LDH assays.
    • To present newer genetic insights and chemotherapy protocols for retinoblastoma.

    Main Methods:

    • Review of diagnostic techniques including ultrasonography, EMI scanning, and anterior chamber LDH assays.

    Related Experiment Videos

  • Discussion of differential diagnoses: larval granulomatosis, Coat's disease, and retinal dysplasias.
  • Analysis of radiation therapy techniques (orthovoltage, 60Co, linear accelerators, betatron) and their associated complications.

    • Main Results:

    • Improved outcomes for Group IV retinoblastoma cases and more extensive study of orbital cases.
    • Identification of radiation dosage-related complications, including vascular necrosis and neoplasms.
    • Demonstration of chemotherapy's role as an adjuvant and for micrometastasis destruction with a new protocol.

    Conclusions:

    • Modern diagnostic and treatment approaches, including advanced imaging and genetic insights, are improving retinoblastoma management.
    • Careful radiation dosage is critical to minimize complications, with inheritance patterns influencing neoplasm risk.
    • Chemotherapy offers a valuable adjunct and treatment for micrometastases, enhancing overall treatment efficacy.