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Gallbladder wall thickening in infectious mononucleosis: an ominous sign
1Department of Radiology, McMaster University Medical Centre, Hamilton, Ontario, Canada.
Abstract:
Gallbladder wall thickening (3 mm or greater) is a nonspecific finding with many causes. We describe two cases caused by infectious mononucleosis. Other causes of gallbladder wall thickening are described and the literature is reviewed. We suggest that the finding of gallbladder wall thickening in a patient with infectious mononucleosis implies that the patient is very ill, and its observation should lead to close patient monitoring.
Insights
Gallbladder wall thickening, a common sign, can stem from various issues. In patients with infectious mononucleosis, this finding indicates severe illness and requires close monitoring.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Radiology
Background:
- Gallbladder wall thickening (≥3 mm) is a nonspecific radiological finding.
- Numerous conditions can cause gallbladder wall thickening.
- Infectious mononucleosis is a potential, though less common, cause.
Observation:
- Two cases of gallbladder wall thickening secondary to infectious mononucleosis are presented.
- The patients' clinical presentations and diagnostic imaging are detailed.
- Literature review on causes of gallbladder wall thickening is included.
Findings:
- Gallbladder wall thickening in infectious mononucleosis suggests significant patient illness.
- This finding is associated with severe presentations of the viral infection.
- Differential diagnoses for gallbladder wall thickening are discussed.
Implications:
- Observing gallbladder wall thickening in infectious mononucleosis warrants heightened clinical vigilance.
- Close patient monitoring is crucial for managing severe infectious mononucleosis.
- This finding may prompt a reevaluation of the patient's overall condition and treatment plan.