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A new non-contact corneal aesthesiometer (NCCA)
P J Murphy1, S Patel, J Marshall
1Department of Vision Sciences, Glasgow Caledonian University, UK.
Summary
This study introduces a new, non-invasive method to measure corneal nerve function by assessing corneal sensitivity using controlled air pulses. The developed aesthesiometer accurately determines the corneal sensitivity threshold in normal eyes.
Area of Science:
- Ophthalmology
- Neuroscience
- Biomedical Engineering
Background:
- Corneal nerve function is crucial for ocular health and sensation.
- Assessing corneal sensitivity is important for diagnosing various eye conditions.
- Current methods for testing corneal sensitivity can be invasive or lack precision.
Purpose of the Study:
- To present a novel, non-invasive method for evaluating corneal nerve function.
- To describe the development and technical specifications of a new aesthesiometer.
- To establish baseline measurements of corneal sensitivity in healthy eyes.
Main Methods:
- A novel aesthesiometer was developed to deliver controlled air pulses to the corneal surface.
- Non-invasive measurement of corneal sensitivity was performed using either the method of constant stimuli or the method of limits.
- The air pressure threshold required for stimulation was recorded in millibars for 14 normal, non-lens wearing eyes.
Main Results:
- The aesthesiometer demonstrated accuracy in locating the corneal sensitivity threshold.
- Mean normal corneal sensitivity threshold was determined to be 0.342 +/- 0.068 millibars of air pressure.
- The instrument's mode of action and technical details were elucidated.
Conclusions:
- The novel aesthesiometer provides a precise and non-invasive means to measure corneal sensitivity.
- This method offers advantages over existing invasive techniques for assessing corneal nerve function.
- The instrument has potential for widespread clinical application in ophthalmology.