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Cutaneous mycoses in children

B E Elewski1

  • 1Department of Dermatology, Case Western Reserve University, Cleveland, OH, 44 USA.

The British Journal of Dermatology
|June 1, 1996
PubMed
Summary
This summary is machine-generated.

This review covers common childhood fungal skin infections. Terbinafine shows promise as a safer alternative to griseofulvin for treating pediatric mycoses, particularly tinea capitis.

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Area of Science:

  • Dermatology
  • Pediatrics
  • Mycology

Background:

  • Common pediatric cutaneous mycoses include candidiasis, pityriasis versicolor, tinea corporis, tinea pedis, onychomycosis, and tinea capitis.
  • Topical therapies are effective for superficial infections but not for tinea capitis, onychomycosis, or in immunocompromised children.

Purpose of the Study:

  • To review current and potential treatments for common pediatric cutaneous mycoses.
  • To evaluate the efficacy and safety of antifungal agents in children.

Main Methods:

  • Review of existing literature on pediatric antifungal therapy.
  • Comparison of griseofulvin, ketoconazole, fluconazole, itraconazole, and terbinafine for treating various pediatric mycoses.

Main Results:

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  • Griseofulvin, the traditional treatment, is fungistatic and has potential drug interactions and long treatment durations.
  • Terbinafine demonstrates a favorable safety profile and efficacy comparable to griseofulvin for tinea capitis, with shorter treatment times.
  • Fluconazole and itraconazole show potential but have limited pediatric data and formulation challenges.

Conclusions:

  • Terbinafine is a promising alternative to griseofulvin for pediatric mycoses due to its safety and efficacy.
  • Further research and pediatric-specific formulations are needed for fluconazole and itraconazole to establish their roles in treating childhood fungal infections.