Shear field mapping in actin networks by using magnetic tweezers
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F G Schmidt1, F Ziemann, E Sackmann
1Physics Department of E22 (Biophysics Group), Technische Universität München, Garching, Germany.
European Biophysics Journal : EBJ
|January 1, 1996
Abstract:
An improved magnetic bead microrheometer based on phase contrast microscopy allowing high resolution measurements of local deformations within macromolecular network is applied to study local viscoelastic properties of cross-linked actin networks. By embedding nonmagnetic colloidal beads as probes into the networks, the spatial variation of the strain field within cross-linked actin networks can be mapped. Moreover, the Poisson ratio and shear modulus can be measured locally.