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Allergic contact dermatitis due to Centella asiatica: a new case
M A Gonzalo Garijo1, F Revenga Arranz, P Bobadilla González
1Allergology Departament, Infanta Cristina University Hospital, Badajoz Spain.
Allergologia Et Immunopathologia
|May 1, 1996
Summary
Allergic contact dermatitis from Centella asiatica is reported. Standardized patch testing with 1% petrolatum is suggested, escalating to 10% petrolatum or 2% ethanol if negative, for accurate diagnosis.
Area of Science:
- Dermatology
- Allergology
- Pharmacology
Background:
- Centella asiatica is a plant used in traditional medicine and cosmetics.
- Allergic contact dermatitis (ACD) is an immune response to external substances.
- Centella asiatica is considered a weak sensitizer, necessitating careful diagnostic approaches.
Observation:
- A new case of allergic contact dermatitis caused by Centella asiatica was identified.
- Patch testing was performed using various concentrations and vehicles of Centella asiatica.
- Patient reactions were monitored to determine optimal testing parameters.
Findings:
- The study evaluated the efficacy of different patch test concentrations and vehicles for Centella asiatica.
- A suggested routine diagnostic protocol involves starting with 1% petrolatum.
- If initial tests are negative, higher concentrations (10% petrolatum) or different vehicles (2% ethanol 70%) are recommended.
Implications:
- Establishing standardized patch testing protocols is crucial for diagnosing Centella asiatica-induced ACD.
- Accurate diagnosis can prevent further exposure and manage allergic reactions effectively.
- These findings contribute to the safe use of Centella asiatica in cosmetic and therapeutic applications.