[Extrapyramidal disorders following sertraline use; experiences with a new selective antidepressant]

In five patients, two women aged 40 and 65 years and three men aged 42, 70 and 84 years, extrapyramidal symptoms such as rigidity and tremors, were considered to be caused by the use of the antidepressant drug sertraline, a serotonin reuptake inhibitor. After discontinuation of the medication the symptoms disappeared.