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[Zinc--update of an essential trace element]
Summary
Zinc is an essential trace element vital for human and animal health. This review covers zinc's absorption, functions, deficiency, toxicity, and dietary recommendations for optimal nutritional status.
Area of Science:
- Nutritional Physiology
- Biochemistry
- Medicine
Context:
- Zinc is recognized as an essential trace element for humans and animals.
- Recent decades have seen significant advancements in understanding zinc's role.
Purpose:
- To review current knowledge on zinc's physiological and biochemical roles.
- To summarize zinc absorption, dietary factors, functions, deficiency, toxicity, and recommendations.
Summary:
- The paper reviews zinc absorption mechanisms, dietary sources, bioavailability factors, and interactions.
- It details zinc's biochemical functions in enzymes, gene expression, and its impact on endocrinology, immunology, and oxidative stress.
- The review also covers signs of zinc deficiency and toxicity, alongside dietary recommendations and status assessment methods.
Impact:
- Provides a comprehensive overview of zinc's importance in health and disease.
- Informs on dietary strategies and clinical assessment for zinc-related conditions.
- Highlights the need for understanding zinc homeostasis for public health and medical practice.