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[D-Ala2,D-Leu5]-enkephalin hydrochloride
J R Deschamps1, C George, J L Flippen-Anderson
1Laboratory for the Structure of Matter, Naval Research Laboratory, Washington, DC 20375, USA. deschamps@lsm.nrl.navy.mil
Abstract:
The title compound, L-tyrosyl-D-alanyl-glycyl-L-phenyl-alanyl-D-leucine hydrochloride (C29H40N5O7+. Cl-), co-crystallizes with 2-butanone (C4H8O). The structure determination reveals a slightly distorted type I' beta-bend conformation stabilized by one intramolecular hydrogen bond. This conformation is similar to that observed for other [Leu]-enkephalin analogues.