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Synthesis and antimicrobial activity of new quaternary ammonium chlorides
B Brycki1, A Skrzypczak, I Mirska
1Department of Chemistry, Adam Mickiewicz University, Poznań, Poland.
Archiv Der Pharmazie
|June 1, 1996
Abstract:
Decyldimethylamine reacts readily with chloromethylalkyl ethers of sulfides, chloromethylbenzyl ethers or sulfides and chloromethylcycloalkyl ethers to give quaternary ammonium chlorides in very good yields. All the chlorides studied showed antimicrobial activity. The relationship between the chemical structure and antimicrobial activity was analyzed by rough sets.