Related Experiment Videos
[Heart involvement in Behcet's disease: a personal caseload en review of the literature]
N Giordano1, M Senesi, S Mondillo
1Istituto di Patologia Speciale Medica, Università Degli Studi di Siena.
Insights
Cardiac abnormalities are more common in Behçet
Area of Science:
- Cardiology
- Rheumatology
- Internal Medicine
Context:
- Behçet's disease is a rare multisystem inflammatory disorder.
- Cardiac involvement in Behçet's disease is infrequently reported.
- Growing awareness has expanded the known spectrum of cardiac manifestations.
Purpose:
- To evaluate cardiac involvement in a cohort of 15 patients with Behçet's disease.
- To assess the prevalence and types of cardiac abnormalities in these patients.
Summary:
- Six out of 15 patients with Behçet's disease exhibited cardiac abnormalities.
- Mitral valve prolapse was the most common finding.
- One patient presented with unexpected dilatative cardiomyopathy.
Impact:
- Suggests that cardiac involvement in Behçet's disease may be more prevalent than previously thought.
- Highlights the importance of regular cardiovascular monitoring, even in asymptomatic patients.
- Contributes to a better understanding of the cardiovascular complications of Behçet's disease.
Backgrounds:
Various cardiac abnormalities have been described in patients with Behçet's disease. The number of reports remains small, but increasing awareness have widened the spectrum of manifestations. We report our evaluation of cardiac involvement in 15 patients affected by Behçet's disease, diagnosed according to the criteria for the International Study Group for Behçet's Disease.
Patients And Methods:
All the patients have been examined by a clinical, biochemical and instrumental point of view. Six patients resulted to be affected by heart diseases, in particular by mitral valve prolapse; moreover one of them presented an unexpected dilatative cardiomyopathy.
Conclusions:
The authors affirm that the pathological heart features are not so uncommon as previously reported in literature, emphasizing the necessity of a constant evaluation for the cardiovascular system also in the asymptomatic patients.