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Synthesis and anticancer properties of pyrimido[4,5-b]quinolines
1Department of Organic Chemistry, University of Medicine, Faculty of Pharmacy, Grodzka, Poland.
Farmaco (Societa Chimica Italiana : 1989)
|May 1, 1996
Abstract:
The synthesis and antitumor properties of pyrimido[4,5-b]quinolines have been described starting from 4-arylamino-5-carboxy-2-hydroxy-6-methylpyrimidines by reaction with PPA or POCl3. The reduced pyrimidoquinolines and derivatives with alkylating function have also been obtained.