[Comparison of dynamic and isometric loading in echocardiographic examinations in patients with ischemic heart

J Spác1, M Blaha, H Nĕmcová

  • 1II. interní klinika FNsP u sv. Anny, Brno.

Vnitrni Lekarstvi
|May 1, 1996
PubMed

Insights

Dynamic echocardiographic load significantly impacts left ventricular function more than isometric load in ischemic heart disease patients. This study compared these loads in patients with varying coronary artery disease severity.

Area of Science:

  • Cardiology
  • Cardiovascular Physiology
  • Diagnostic Imaging

Background:

  • Ischemic heart disease (IHD) affects myocardial function.
  • Assessing left ventricular (LV) function under stress is crucial for IHD management.
  • Different echocardiographic load types may elicit varied responses.

Purpose of the Study:

  • Compare LV functional indicators during isometric (HG) and dynamic (Ergo) echocardiographic stress tests.
  • Evaluate responses in patients with different severities of coronary artery disease (CAD).
  • Determine which load type provides more significant functional changes.

Main Methods:

  • Echocardiography with isometric (handgrip) and dynamic (ergometer) stress.
  • Inclusion of 34 patients with three-vessel CAD (Group A) and 15 with one-to-two-vessel CAD (Group B).
  • Measurement of blood pressure, heart rate, LV volumes (EDV/m², ESV/m²), Limacher's index, and ejection fraction (EF) at rest and post-load.

Main Results:

  • Both loads increased LV end-diastolic and end-systolic volumes; dynamic load caused greater increases.
  • Ejection fraction decreased under both loads, with a more pronounced drop during dynamic stress.
  • Dynamic load induced a statistically significant drop in Limacher's index and greater volumetric changes in patients with less severe CAD (1-2 vessels).
  • In severe CAD (3 vessels), isometric load produced volumetric changes comparable to dynamic load.

Conclusions:

  • Dynamic echocardiographic load is a more potent stressor than isometric load for evaluating LV function in IHD.
  • The severity of CAD influences the LV response to different echocardiographic stress types.
  • Findings aid in selecting appropriate stress modalities for IHD assessment.

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