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[Keratomycoses]
E Ríhová1, M Havlíková, J Boguszaková
1I. ocní klinika 1. LF UK, Praha.
Abstract:
Mycotic inflammations of the anterior segment of the eye are relatively rare in our geographical zone. The clinical picture, isolation of the pathogenic organism and possible treatment are discussed with reference to three patients with keratomycosis treated at the First Ophthalmological Clinic of the First Medical Faculty, Charles University Prague. Microscopic examination of the affected tissue revealed Fusarium 1x and Candida alb. also on cultivation. Natamycin 5.0% suspension cured Fusarium keratitis and improved the symptoms of Candida infection. In two patients perforating keratoplasty was necessary in one instance because of imminent perforation of a posterior mycotic corneal abscess and in the second patient because of subsequent bacterial reinfection.
Insights
Mycotic eye inflammation, or keratomycosis, is rare. Natamycin successfully treated Fusarium infections and aided Candida cases, with surgery needed for severe complications.
Area of Science:
- Ophthalmology
- Mycology
- Infectious Diseases
Background:
- Mycotic keratitis, an infection of the cornea, is uncommon in many regions.
- This study examines three cases of anterior segment mycotic inflammation.
Observation:
- Patients presented with clinical signs of keratomycosis.
- Microscopic and culture analyses identified Fusarium and Candida albicans as causative agents.
Findings:
- Natamycin 5.0% suspension effectively treated Fusarium keratitis.
- Natamycin improved symptoms in Candida albicans infections.
- Surgical intervention, including keratoplasty, was required for two patients due to complications like abscesses and secondary bacterial infections.
Implications:
- Early diagnosis and targeted antifungal therapy are crucial for managing mycotic keratitis.
- Aggressive management, potentially including surgery, may be necessary for severe or complicated cases.
- Understanding the clinical presentation and treatment outcomes aids in managing these rare ocular infections.