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Epidemics of haemorrhagic cystitis due to influenza A virus
Postgraduate Medical Journal
|May 1, 1977
Abstract:
The present communication describes studies on thirty-three patients with haemorrhagic cystitis. The current epidemic variant of influenza type A virus, A/Tehran/5/75 (H3N2) [antigenically similar to A/Port Chalmers/1/73 (H3N2)], was recovered from the throats of eighteen and the urine of three patients. HI antibody rises to A/Tehran/5/75 virus were detected in over 50% of the cystitis patients tested.
Insights
Influenza A virus (H3N2) was identified in patients with hemorrhagic cystitis. Antibody responses to the virus were observed in over half of the patients studied.
Area of Science:
- Virology
- Infectious Diseases
- Urology
Background:
- Hemorrhagic cystitis is a condition affecting the bladder.
- Influenza A virus is a common respiratory pathogen.
Purpose of the Study:
- To investigate the potential role of influenza A virus in hemorrhagic cystitis.
- To identify the etiological agent in patients with hemorrhagic cystitis.
Main Methods:
- Patient sample collection (throat and urine).
- Viral isolation and identification.
- Hemagglutination inhibition (HI) antibody testing.
Main Results:
- Influenza A virus (H3N2), A/Tehran/5/75, was isolated from 18 throat and 3 urine samples.
- Over 50% of patients showed a rise in HI antibodies to the virus.
Conclusions:
- Influenza A virus (H3N2) may be implicated in the development of hemorrhagic cystitis.
- Further research is warranted to confirm the causal link.