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Summary
Hepatitis-associated antigen (HAA) in virus-like particles is linked to serum hepatitis transmission. Even undetectable HAA levels in materials can cause hepatitis infection.
Area of Science:
- Hepatology
- Virology
- Immunology
Background:
- Serum hepatitis (serum-borne viral hepatitis) is a significant public health concern.
- The causative agent of serum hepatitis was suspected to be a transmissible particle.
- Australia antigen, later termed hepatitis B surface antigen, was identified as a potential marker.