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Intracarotid blood pressure changes during contrast medium injection
H Saitoh1, K Hayakawa, K Nishimura
1Department of Radiology, Kyoto City Hospital, Japan.
AJNR. American Journal of Neuroradiology
|January 1, 1996
Summary
Intracarotid injection of contrast material temporarily increases cerebral blood pressure in dogs. This effect is dose- and rate-dependent, regardless of catheter position.
Area of Science:
- Neurology
- Radiology
- Vascular Biology
Background:
- Intracarotid injections are common in diagnostic imaging.
- Understanding hemodynamic effects is crucial for patient safety.
- Cerebral blood pressure (CBP) regulation is complex.
Purpose of the Study:
- To quantify changes in cerebral blood pressure during intracarotid contrast material injection.
- To assess the relationship between injection parameters and CBP elevation.
Main Methods:
- Two catheters were placed in the ipsilateral common carotid artery of canine models.
- Contrast material was injected via a proximal catheter.
- Blood pressure was monitored distally using a second catheter.
Main Results:
- Significant increases in distal intracarotid pressure were observed during contrast injection.
- Elevations in blood pressure correlated directly with injection rates and doses.
- Pressure changes persisted even when the monitoring catheter was advanced into smaller arteries.
Conclusions:
- Intracarotid contrast injection leads to transient elevations in cerebral blood pressure in dogs.
- These findings highlight potential hemodynamic risks associated with the procedure.
- Further research may inform safer contrast administration protocols.