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Perineural spread of rhinocerebral mucormycosis
F M McLean1, L E Ginsberg, C A Stanton
1Department of Radiology, Bowman Gray School of Medicine, Winston-Salem, NC 27157-1088, USA.
AJNR. American Journal of Neuroradiology
|January 1, 1996
Abstract:
An unusual pathway of local spread of rhinocerebral mucormycosis is presented with MR and pathologic correlation. Perineural extension, proved with pathology, followed the trigeminal nerve to the pons. Enhancement of the nerve was seen on MR.
Insights
Rhinocerebral mucormycosis can spread unusually along the trigeminal nerve to the brainstem. Magnetic resonance imaging (MR) showed nerve enhancement, confirmed by pathology, revealing perineural extension.
Area of Science:
- Medical Mycology
- Neuroradiology
- Pathology
Background:
- Rhinocerebral mucormycosis is a severe fungal infection.
- Local spread patterns are crucial for understanding disease progression.
- The trigeminal nerve's involvement is an uncommon route of central nervous system invasion.