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Gender differences in percutaneous interventional therapy of coronary artery disease
1Department of Medicine, Northwestern Memorial Hospital, Northwestern University Medical School, Chicago, Illinois 60611, USA.
Insights
Men and women undergoing revascularization for coronary heart disease showed similar angiographic characteristics and outcomes. However, men were more likely to receive new devices during percutaneous intervention.
Area of Science:
- Cardiology
- Interventional Cardiology
- Gender Differences in Medicine
Background:
- Coronary heart disease (CHD) affects both men and women, but treatment patterns and outcomes may differ.
- Revascularization therapies, including percutaneous intervention and coronary artery bypass surgery, are common treatments for CHD.
- Understanding potential gender-based differences in angiographic parameters is crucial for optimizing patient care.
Purpose of the Study:
- To investigate gender-specific differences in angiographic parameters among patients undergoing revascularization for coronary heart disease.
- To compare demographic, clinical, and angiographic characteristics between men and women.
- To evaluate outcomes of percutaneous intervention and coronary artery bypass surgery in relation to gender.
Main Methods:
- Retrospective review of patients diagnosed with cardiac ischemic syndrome.
- Analysis of demographic, clinical, and angiographic data, including body surface area, lesion distribution, and vessel size.
- Comparison of outcomes for percutaneous intervention and coronary artery bypass surgery between male and female patients.
Main Results:
- No significant differences were observed in vessel distribution, size, or procedural outcomes between men and women undergoing percutaneous revascularization.
- While baseline angiographic characteristics were similar, men were more likely to receive a new device during percutaneous intervention.
- No differences were found in patient selection for percutaneous intervention among those who underwent coronary arteriography.
Conclusions:
- Gender does not appear to influence baseline angiographic characteristics or outcomes in patients undergoing percutaneous revascularization for coronary heart disease.
- Men undergoing percutaneous intervention were more likely to utilize new devices, suggesting potential gender-based variations in treatment approach.
- Further research is warranted to explore the reasons behind the observed differences in device utilization and the lower rates of coronary arteriography and bypass surgery in women.
Abstract:
To determine what differences exist in angiographic parameters between men and women undergoing revascularization therapy for coronary heart disease that may indicate a gender difference, a retrospective review of patients admitted to one hospital for diagnosis of cardiac ischemic syndrome, and undergoing coronary arteriography, percutaneous interventional procedure, or coronary bypass surgery, was performed. Demographic, clinical, and angiographic parameters were evaluated in men and women, including body surface area, distribution of coronary lesions, size of target coronary vessels, and results of interventional procedures. Men and women undergoing percutaneous revascularization did not differ in regard to distribution or size of vessels or outcome. Previous data support the contention that women may undergo coronary arteriography and coronary artery bypass surgery less frequently than men. No evidence of differences existed in selecting patients for percutaneous intervention from those patients who underwent coronary arteriography. Men and women who underwent percutaneous intervention had similar baseline angiographic characteristics, yet men were more likely to receive a new device.