AV node reentry tachycardia in infants
J E Crosson1, P S Hesslein, O G Thilenius
1Department of Pediatrics, University of Minnesota Hospital, Minneapolis, USA.
Insights
Atrioventricular (AV) node reentry tachycardia occurs in infants with structurally normal hearts. This condition can manifest early in life, even in newborns, and may require intervention.
Area of Science:
- Pediatric Cardiology
- Electrophysiology
- Cardiac Arrhythmias
Background:
- Paroxysmal tachycardia is a common concern in infants.
- Transesophageal electrophysiological study is a diagnostic tool for pediatric arrhythmias.
- Atrioventricular (AV) node reentry tachycardia is a specific type of supraventricular tachycardia.
Purpose of the Study:
- To determine the frequency of AV node reentry tachycardia in infants.
- To analyze the characteristics and clinical presentation of AV node reentry tachycardia in this age group.
- To assess the early onset and potential recurrence of AV node reentry tachycardia in infants.
Main Methods:
- Retrospective review of 52 infants under 1 year old with structurally normal hearts undergoing transesophageal electrophysiological study for paroxysmal tachycardia.
- Detailed data review and follow-up (>12 months) for infants diagnosed with AV node reentry tachycardia.
- Analysis of electrophysiological parameters including tachycardia cycle length and ventriculoatrial intervals.
Main Results:
- Six of 52 infants (11.5%) were diagnosed with AV node reentry tachycardia.
- Tachycardia was diagnosed at a mean age of 2.1 months, with 3 infants studied within the first month of life.
- Recurrences were observed in 2 of 6 patients during a mean follow-up of 24 months; 5 of 6 showed discontinuous AV node conduction.
Conclusions:
- The substrate for AV node reentry tachycardia is present early in infancy.
- AV node reentry tachycardia is a clinically significant arrhythmia in newborns and young infants.
- Early diagnosis and management are crucial for infants presenting with paroxysmal tachycardia.
Abstract:
The purpose of this study was to determine the frequency of atrioventricular (AV) node reentry tachycardia in infants undergoing transesophageal electrophysiological study for paroxysmal tachycardia. The records of all 52 infants < 1-year-old with structurally normal hearts who underwent transesophageal study for paroxysmal tachycardia over a 3-year period were reviewed. Those with a diagnosis of AV node reentry tachycardia underwent complete data review, and follow-up of > 12 months was obtained. Six of 52 infants had a diagnosis of the common type of AV node reentry tachycardia. Tachycardia was diagnosed at a mean age of 2.1 months (range 1 day to 10 months), and 3 of 6 underwent transesophageal study within the first month. Although no patient had structural heart disease, three patients had significant noncardiac disease. Follow-up of 15-38 months (mean 24 +/- 7.8) revealed recurrences in 2 of 6 patients. The mean tachycardia cycle length was 240 ms (range 200-310 ms), and the transesophageal ventriculoatrial intervals ranged from < 30 to 55 ms. All patients had a inducible reentrant tachycardia with a ventriculoatrial interval that remained constant even when tachycardia cycle length increased following verapamil or adenosine administration, or decreased following isoproterenol infusion. Five of 6 had evidence for discontinuous AV node conduction curves. In our patients the substrate for AV node reentry tachycardia was present early in life, and AV node reentry tachycardia can be a clinical problem even in the newborn period.
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