Thought disorder, perceptual aberrations, and schizotypy
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Updated: Nov 4, 2026

Investigating the Effects of Antipsychotics and Schizotypy on the N400 Using Event-Related Potentials and Semantic Categorization
Published on: November 19, 2014
M J Coleman1, D L Levy, M F Lenzenweger
1Department of Psychiatry, Harvard Medical School, Belmont, Massachusetts, USA.
Abstract:
Empirical links between schizophrenia and schizotypic psychopathology were examined. The Perceptual Aberration Scale (PerAb; L. J. Chapman, J. O. Chapman, & M. L. Raulin, 1978) was used to identify putative schizotypic individuals and a contrast group of nonschizotypic controls. The Thought Disorder Index (TDI; M. J. Coleman et al., 1993) was used to quantify and classify thought disorder in these individuals. High PerAb participants, selected for having an increased number of self-reported perceptual and body image aberrations, showed an elevation in the amount and frequency of thought disorder as well as an increased number of idiosyncratic verbalizations. This supports the hypothesis that psychometrically identified schizotypic individuals display thought disorder similar to that shown by schizophrenic patients and some of their 1st-degree relatives, suggesting that there is a relation between schizotypic psychopathology, as tapped by the PerAb scale, and clinical schizophrenia.
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