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Motor neurone disease like picture in hyperthyroidism
R K Patial1, V Kumar, R Kumari
1Department of Medicine, Indira Gandhi Medical College, Shimla.
Indian Journal of Medical Sciences
|May 1, 1995
Summary
Hyperthyroidism can mimic Motor Neurone Disease (MND) in male patients. Prompt treatment with antithyroid drugs resolved MND-like symptoms, highlighting the importance of excluding hyperthyroidism in such cases.
Area of Science:
- Neurology
- Endocrinology
Background:
- Motor Neurone Disease (MND) presents with progressive neurodegeneration.
- Hyperthyroidism is a common endocrine disorder with diverse clinical manifestations.
Purpose of the Study:
- To describe cases of hyperthyroidism presenting with MND-like symptoms.
- To emphasize the need to differentiate hyperthyroidism from MND.
Main Methods:
- Retrospective review of five male patients over five years.
- Clinical assessment and diagnosis of hyperthyroidism and MND-like features.
- Treatment with antithyroid drugs.
Main Results:
- All five patients were male and had symptoms for over three years.
- One patient was initially diagnosed with MND.
- MND-like symptoms resolved within 1-3 months of antithyroid treatment.
Conclusions:
- Hyperthyroidism should be considered in the differential diagnosis of MND-like presentations.
- Early diagnosis and treatment of hyperthyroidism can reverse neurological deficits.