Guillain Barre syndrome-electrodiagnostic features and therapeutic observations

Thirty seven patients with Guillain Barre syndrome were studied. The most common electrophysiologic abnormalities were delayed or absent Median nerve F wave (93.3%), increase in posterior tibial nerve distal latency (91.9%) and delayed or absent posterior tibial nerve F waves (83.9%). Slowing of nerve conduction was associated with the F wave abnormality and distal latency prolongation in most cases. There was no definite relationship between the results of electrophysiological studies and the clinical grade. 15 patients were treated with steroids, 10 with plasmapheresis, 8 with both steroids and plasmapheresis and 3 with immunoglobulins. There was a greater degree of improvement in patients treated with plasmapheresis.