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Systemic lupus erythematosus in males

S Vaidya1, M Y Nadkar, R S Samant

  • 1Dept of Medicine & Rheumatology, TNM College, Bombay.

The Journal of the Association of Physicians of India
|November 1, 1995
PubMed
Summary

This study analyzed twelve male patients with Systemic Lupus Erythematosus (SLE), a condition predominantly affecting women. Arthritis was the most common symptom, and over 40% experienced kidney issues.

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Area of Science:

  • Rheumatology
  • Internal Medicine
  • Genetics

Background:

  • Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease predominantly affecting women.
  • While rare, male cases of SLE have been documented, highlighting the need for further investigation into sex-specific disease characteristics.
  • Understanding variations in SLE presentation across different populations is crucial for accurate diagnosis and treatment.

Purpose of the Study:

  • To analyze the clinical characteristics and manifestations of Systemic Lupus Erythematosus (SLE) specifically in male patients.
  • To identify the most frequent symptoms and organ involvements in a cohort of male SLE patients.
  • To contribute to the understanding of SLE epidemiology and potential sex-based differences in disease presentation.

Main Methods:

  • Retrospective analysis of a cohort of 175 Systemic Lupus Erythematosus (SLE) patients.
  • Detailed review of medical records for twelve identified male patients within the cohort.
  • Documentation and categorization of clinical manifestations, including arthritis and renal involvement.

Main Results:

  • Out of 175 SLE patients, twelve (approximately 6.86%) were identified as male.
  • Arthritis was the most frequently observed clinical manifestation among the male patients.
  • Renal involvement was a significant finding, present in 41.65% of the male SLE patient cohort.

Conclusions:

  • Male patients represent a small but distinct subgroup within the Systemic Lupus Erythematosus (SLE) population.
  • Arthritis and renal involvement are key clinical features to consider in the diagnosis and management of SLE in men.
  • Further research is warranted to elucidate the specific pathophysiology and long-term outcomes of SLE in males.

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