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Nonenhancing primary central nervous system lymphoma

S Terae1, A Ogata

  • 1Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan.

Neuroradiology
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

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Primary central nervous system lymphoma (PCNSL) is rare but increasing. This study reports a rare case of PCNSL presenting as multiple nonenhancing lesions on MRI in an immunocompetent individual.

Area of Science:

  • Neurology
  • Radiology
  • Oncology

Background:

  • Primary central nervous system lymphoma (PCNSL) is a rare malignancy.
  • The incidence of PCNSL has been rising in recent years.
  • Radiological imaging, particularly MRI, is crucial for PCNSL diagnosis.

Observation:

  • PCNSL typically enhances with contrast agents on CT and MRI.
  • Nonenhancing PCNSL is considered exceptionally rare in medical literature.
  • This case involves an immunocompetent patient with PCNSL.

Findings:

  • The presented PCNSL case exhibited multiple nonenhancing lesions on MRI.
  • This finding challenges the conventional understanding of PCNSL radiological presentation.
  • The lesions did not show contrast enhancement, which is atypical for PCNSL.

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Implications:

  • This case expands the spectrum of radiological appearances for PCNSL.
  • It highlights the importance of considering PCNSL even with nonenhancing lesions.
  • Further research may be needed to understand the characteristics and diagnostic criteria for nonenhancing PCNSL.