Related Experiment Video
Updated: Jun 29, 2026
In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Technical note--approach to myocardial perfusion with echo planar imaging
Purpose:
To evaluate the feasibility of MRI-based myocardial first-pass contrast perfusion imaging with a multi-shot echo planar imaging (EPI) technique.
Subjects And Methods:
A non-sequential (ECG-triggered) gradient echo two-shot EPI acquisition strategy capable of covering the entire heart in contiguous 10-mm sections every two cardiac cycles with an in-plane resolution of 1.56 X 1.56 mm was implemented on a 1.5-T Signa Advantage Scanner equipped with prototype hardware for non-resonant EPI in the transverse plane. The heart of a single volunteer was studied prior to and following the intravenous bolus application of a paramagnetic contrast agent (Gd-DOTA, 0.2 mmol/kg).
Results:
Twelve contiguous transaxial 10-mm EPI images were obtained every two RR intervals for a total of 40 s. The myocardial contrast perfusion study was technically adequate. Contrast caused a signal loss of 87% in the right and 67% in the left ventricle and 59% in the myocardium.
Conclusion:
First-pass myocardial perfusion imaging with a gradient echo, two-shot echo planar imaging strategy is feasible.
