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Updated: Aug 11, 2026

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
Published on: July 1, 2020
[Infections of a fungal etiology in the cancer clinic]
Abstract:
Candida fungi, more than half of which are Candida albicans, are responsible for up to 28% of microflora contaminating the pathological material during infectious processes coursing in cancer patients. They may be isolated as a monoculture or in associations with bacteria, depending on the localization of the process. In both cases their pathogenetic significance is really great, which is confirmed by the efficacy of antimycotic therapy and prophylactic measures. The prevalence of fungal infections necessitates taxonomic identification of the isolated fungal cultures.
Insights
Candida fungi, including Candida albicans, frequently contaminate cancer patients, causing infections. Accurate identification of these fungal pathogens is crucial for effective treatment and prevention strategies.
Area of Science:
- Mycology
- Oncology
- Infectious Diseases
Background:
- Candida species are common contaminants in pathological samples from cancer patients, accounting for up to 28% of microflora.
- These fungi can be isolated alone or with bacteria, highlighting their significant role in infectious processes.
- The effectiveness of antifungal therapies confirms the pathogenic importance of Candida in this population.
Purpose of the Study:
- To emphasize the necessity of accurate taxonomic identification of fungal cultures.
- To highlight the prevalence and significance of Candida infections in cancer patients.
Main Methods:
- Isolation and identification of fungal cultures from pathological materials.
- Analysis of contamination rates and co-occurrence with bacterial species.
Main Results:
- Candida species, predominantly Candida albicans, are found in a significant proportion of pathological samples from cancer patients.
- Fungal contamination can occur as a monoculture or in association with bacteria.
Conclusions:
- The high prevalence of Candida infections in cancer patients underscores the need for precise identification methods.
- Effective antimycotic therapy and prophylactic measures are essential for managing these infections.
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