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Related Experiment Videos

Diffuse idiopathic skeletal hyperostosis (DISH): a retrospective analysis

N Pappone1, C Di Girolamo, A Del Puente

  • 1Rheumatology Unit, University Federico II of Naples-Italy.

Clinical Rheumatology
|March 1, 1996
PubMed
Summary
This summary is machine-generated.

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Diffuse idiopathic skeletal hyperostosis (DISH) is a spinal disease. This study found unique patterns in Campania, suggesting microtrauma and metabolic disorders play roles, possibly influenced by genetics.

Area of Science:

  • Rheumatology
  • Orthopedics
  • Radiology

Background:

  • Diffuse idiopathic skeletal hyperostosis (DISH) is a condition causing abnormal bone growth.
  • It primarily affects the spine's ligaments, particularly on the anterolateral side.
  • Previous research provides a baseline for understanding DISH prevalence and characteristics.

Purpose of the Study:

  • To investigate the clinical and radiological features of DISH in a specific population.
  • To compare findings with existing literature on DISH.
  • To explore potential contributing factors like occupation and metabolic disorders.

Main Methods:

  • Retrospective analysis of spinal radiographs from 69 patients diagnosed with DISH.
  • Patients were classified according to Resnick's criteria.

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  • Data collected included patient demographics, extent of hyperostosis, and presence of metabolic disorders.

    • Main Results:

    • A lower rate of lumbar spine involvement (71%) was observed compared to literature.
    • A distinct sex distribution was noted.
    • Associations between hyperostosis extent, occupation, and metabolic disorders were explored.

    Conclusions:

    • The study highlights unique characteristics of DISH in the Campania population.
    • Microtrauma and metabolic disorders appear to be significant factors in DISH pathogenesis.
    • Genetic factors may influence the observed peculiarities in this population.