Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Chronic venous insufficiency]

G Hauer1, J Staubesand, Y Li

  • 1Chirurgische Abteilung, Krankenhaus Weilheim.

Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen
|May 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correlation of the Histological ICRS II Score and the 3D MOCART Score for the Analysis of Aged Osteochondral Regenerates in a Large Animal Model.

Cartilage·2022
Same author

Evaluation of the influence of platelet-rich plasma (PRP), platelet lysate (PL) and mechanical loading on chondrogenesis in vitro.

Scientific reports·2021
Same author

Combined serum biomarker analysis shows no benefit in the diagnosis of periprosthetic joint infection.

International orthopaedics·2020
Same author

Lumican is upregulated in osteoarthritis and contributes to TLR4-induced pro-inflammatory activation of cartilage degradation and macrophage polarization.

Osteoarthritis and cartilage·2019
Same author

Risk factors for heterotopic ossification and spur formation after total knee arthroplasty.

Archives of orthopaedic and trauma surgery·2014
Same author

Microporous calcium phosphate ceramics as tissue engineering scaffolds for the repair of osteochondral defects: Histological results.

Acta biomaterialia·2013
Same journal

[S3 Guideline "Adult soft tissue sarcomas"].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Synopsis-S3 guidelines pancreatic cancer].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Laparoscopic sentinel node navigation surgery in gastric cancer to reduce surgical radicality].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Future concepts for neoadjuvant and adjuvant treatment of (resectable) pancreatic cancer].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[ASCO guidelines for the treatment of stage III NSCLC part 4: indications for adjuvant therapy].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
Same journal

[Surgical treatment of pancreatic cancer-What is new?]

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2022
See all related articles

Severe chronic venous insufficiency (CVI) involves the leg fascia, increasing compartment pressure and impairing circulation. Surgical interventions like fasciotomy and fasciectomy are crucial for healing crural ulcers.

Area of Science:

  • Vascular Surgery
  • Anatomy
  • Pathophysiology

Background:

  • Severe chronic venous insufficiency (CVI) significantly impacts the fascia cruris, altering its texture and reducing lower extremity compartment compliance.
  • This leads to elevated compartment pressures, impaired microcirculation, and functional deficits in arteries and nerves.
  • The fascia cruris serves as the anatomical substrate for many pathological changes observed in crural ulcers.

Purpose of the Study:

  • To elucidate the role of fascia cruris involvement in severe chronic venous insufficiency (CVI).
  • To correlate fascial changes with pathological alterations in crural ulcers.
  • To outline therapeutic strategies based on the understanding of fascial pathophysiology in CVI.

Main Methods:

  • Review of pathological processes in severe CVI affecting the fascia cruris.

Related Experiment Videos

  • Analysis of the relationship between fascial texture, compartment pressure, and microcirculation.
  • Evaluation of therapeutic interventions including fasciotomy, fasciectomy, and plastic surgery.
  • Main Results:

    • Altered fascia cruris texture in CVI leads to loss of compliance and increased compartment pressure.
    • Increased pressure functionally impairs arteries, nerves, and perforating veins.
    • Microcirculation is compromised by both primary varicosis with secondary deep vein insufficiency and primary deep venous system insufficiency (e.g., post-thrombotic syndrome).

    Conclusions:

    • Therapeutic strategies for CVI must address fascial involvement, incorporating medication, physical therapy, and surgical interventions.
    • Endoscopic fasciotomy and dissection of perforating veins are state-of-the-art for managing insufficient perforating veins.
    • In severe cases, fasciectomy combined with plastic surgery offers a pathway to durable healing of crural ulcers.