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Kikuchi's disease associated with Hashimoto's thyroiditis
S I Rubio1, T S Plewinsky, M Sabatini
1Department of Medicine, Cabrini Medical Center, New York Medical College, New York, USA.
Journal of Endocrinological Investigation
|February 1, 1996
Summary
This case report details a rare co-occurrence of Kikuchi's disease and Hashimoto's thyroiditis. Diagnostic lymph node biopsy and thyroid aspiration clarified the link between the patient's goiter and lymphadenopathy.
Area of Science:
- Immunology
- Pathology
- Endocrinology
Background:
- Histiocytic necrotizing lymphadenitis, also known as Kikuchi's disease, is a rare, benign condition characterized by fever and lymphadenopathy.
- Chronic lymphocytic thyroiditis, or Hashimoto's thyroiditis, is an autoimmune disease leading to hypothyroidism and goiter.
Observation:
- A patient presented with concurrent cervical lymphadenopathy and a goiter, prompting investigation into the underlying causes.
- The clinical presentation suggested a potential link between the lymphadenopathy and thyroid enlargement.
Findings:
- A unique association between Kikuchi's disease and Hashimoto's thyroiditis was identified in this patient.
- Lymph node biopsy confirmed histiocytic necrotizing lymphadenitis, while fine needle aspiration revealed chronic lymphocytic thyroiditis.
Implications:
- This case highlights the importance of considering co-existing conditions in patients with complex presentations.
- Combined diagnostic procedures, including lymph node biopsy and thyroid fine needle aspiration, are crucial for accurate diagnosis.
- Understanding this association may improve diagnostic approaches for patients presenting with both lymphadenopathy and goiter.